Research

Seeing cancer in the genome's dark matter.

I build the computational tools to read the 98% of the genome that doesn't code for proteins, hunting the non-coding driver mutations behind breast cancer.

Research focus

Threads I'm pulling.

Where the epigenome, machine learning and a little curiosity meet cancer medicine.

Non-Coding Driver Mutations

Investigating the 98% non-coding genome to find regulatory mutations that drive breast cancer progression, using more than 5,000 whole genomes from TCGA and ICGC.

Deep Learning for Genomics

Developing CNNs, GNNs, MLPs and Hidden Markov Models to predict chromatin accessibility and prioritise candidate driver mutations from multi-omics data.

3D Regulatory Mapping

Building breast tissue-specific regulatory maps by integrating single-cell ATAC-seq, spatial transcriptomics and ENCODE regulatory elements.

Surgical Robotics & Embedded AI

Exploring Arduino and ESP32 prototyping as a practical bridge from machine learning research into surgical robotics and autonomy workflows.

Currently exploring

Why this work matters

Most disease variants hide in the non-coding genome.

Almost every common cancer-risk variant lives in the 98% we used to call junk. If we can finally read it, we can find the mutations that rewire a healthy cell into a tumour, and the vulnerabilities that could treat it. That's the bet my whole PhD is built on.

Publications

Research & publications.

Deciphering the Non-coding Cancer Genome through Deep Learning and Multiomic Integration

2026

Deciphering the Non-coding Cancer Genome through Deep Learning and Multiomic Integration

Faith Ogundimu, Simon J. Furney

Submitted to npj Genomic Medicine

๐Ÿ“ Under review
BioSLATE: Biomarker Selection and Synthetic Lethality Analysis for Therapeutic Exploration in HGSOC

2025

BioSLATE: Biomarker Selection and Synthetic Lethality Analysis for Therapeutic Exploration in HGSOC

Faith Ogundimu, Metin Yazar, Colm J. Ryan

Breakthrough Cancer Research Summer Student Scholarship

๐Ÿ… Best Lay Presentation๐Ÿ… 30/30 Poster
Using Neural Networks and Foundation Models to Understand Gene Regulation in the MCF-7 Breast Cancer Cell Line

2025

Using Neural Networks and Foundation Models to Understand Gene Regulation in the MCF-7 Breast Cancer Cell Line

Faith Ogundimu, Simon J. Furney

Final Year Dissertation, Dublin City University

๐ŸŽ“ 98% Model Accuracy

Let's talk

Let's decode something.

Collaborations, questions, or just curious about the non-coding genome? My inbox is open.